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Design and construction of a blood fractionation plant in Brazil


As part of a technology transfer between the LFB (French fractionation and biotechnology laboratory) and a state-owned company in Latin America, our biotechnology experts at Boccard worked on the design and construction of a blood fractionation plant.

For the construction of this blood fractionation plant, Boccard was chosen as the supplier of the process equipment. The factory has a surface area of 48,000m² with 17 buildings, including 10,000m² of clean rooms and a production capacity of 500,000 L / year.

Boccard designed and built all the process equipment and also ensured the design of all the fluid distribution networks on a 3D model, as well as all the automation architecture networks. This production unit is also equipped with protein purification and separation skids (Ultra Filtration, Chromatography, Nano Filtration, Centrifugation, Frontal filtration, etc.).

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Key points

Production capacity of 500,00L / year

30,000 hours of engineering and design

100,000 hours of construction

25 km of utility pipes

10,000 input / output


  • 8 ultra-filtration skids
  • 4 skids for Nano Filtration
  • 18 CIP skids and associated distribution
  • 15 water loops and sub-loops
  • 150 P&ID
  • 10,000 input / output
  • 240 stainless steel process vessels – 60 automatons
  • 25 km of utility pipes
  • Centrifugal separation, chromatography, precipitation

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