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Our Achievements

PHARMA & BIOTECH

Turnkey cell culture plant in Malaysia

project essentials

Alpha Biologics, a biotech laboratory in Malaysia, turned to Boccard for the design and construction of a complete plant dedicated to cell culture.

key elements

Greenfield EPC factory
Complete design of the factory: process, clean rooms, building
5,000 m² of building area
2,500 m² of cleanrooms
10 bioreactor skids

EQUIPEMENT supplied

Upstream process

3 cell inoculation laboratories

1 upstream fermentation zone

2 harvest rooms

Equipment provided

10 bioreactor skids including:

  • 4 bioreactors of 10L
  • 2 bioreactors of 70L
  • 2 bioreactors of 250L
  • 1 bioreactor of 500L

4 chromatography modules

6 ultra-filtration modules

1 preparation tank

Downstream process

2 downstream purification suites

1 final downstream filtration zone

for further information

Boccard carried out this entire greenfield project - whether it was the design, construction and commissioning of the plant - with a global contractor approach, thus integrating civil engineering, clean rooms, as well as all production units (including 10 bioreactors, chromatography and ultrafiltration modules in the form of "plug-and-play" skids)

The final project includes 3 cell inoculation laboratories, 1 upstream fermentation zone, 2 harvest rooms, as well as 2 downstream purification suites, 1 downstream final filtration zone. Boccard also designed the quality control laboratory and the process development area, as well as the supply of its own utility networks and standard utilities

The geographical presence of Boccard, with a business unit in Malaysia, and the proximity and availability of the production teams were a real asset for this project. Boccard's expertise in fermentation enabled process control throughout the project.

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