{"id":95820,"date":"2026-10-30T14:37:12","date_gmt":"2026-10-30T14:37:12","guid":{"rendered":"https:\/\/www.boccard.com\/scale-up-en-fermentation-grace-a-une-installation-multi-bioreacteurs-de-50-a-5-000-l\/"},"modified":"2026-10-30T15:55:43","modified_gmt":"2026-10-30T15:55:43","slug":"scale-up-en-fermentation-grace-a-une-installation-multi-bioreacteurs-de-50-a-5-000-l","status":"publish","type":"post","link":"https:\/\/www.boccard.com\/fr\/scale-up-en-fermentation-grace-a-une-installation-multi-bioreacteurs-de-50-a-5-000-l\/","title":{"rendered":"Scale up en fermentation gr\u00e2ce \u00e0 une installation multi-bior\u00e9acteurs de 50 \u00e0 5 000 L"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"95820\" class=\"elementor elementor-95820 elementor-95799\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4160cf5c elementor-section-full_width 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l21.2-4.5c2,2.8,5.4,4.5,9.3,4.5c6.4,0,11.2-4.6,11.2-10.6C65.3,52.7,65.2,52.4,65.2,52.1L65.2,52.1z\"><\/path>\t\t<\/g>\t<\/g><\/g><\/svg>\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t<div class=\"elementor-icon-box-content\">\n\n\t\t\t\t\t\t\t\t\t<h3 class=\"elementor-icon-box-title\">\n\t\t\t\t\t\t<span  >\n\t\t\t\t\t\t\tFOOD<br \/>&amp; INGREDIENTS\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-5ad2b619 bg-over elementor-hidden-mobile\" data-id=\"5ad2b619\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-59001e41 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"59001e41\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-33345bb1\" data-id=\"33345bb1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6a0b33c3 elementor-widget elementor-widget-text-editor\" data-id=\"6a0b33c3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Boccard d\u00e9veloppe actuellement, dans le cadre de son offre <a href=\"https:\/\/www.boccard.com\/fr\/solutions\/tekinbio-fermenteur-pour-de-micro-organismes\/\">TEKINBIO\u2122,<\/a> une installation biotechnologique <a href=\"https:\/\/www.boccard.com\/fr\/solutions\/prefabrication-de-skids\/\">modulaire<\/a> pour un client d\u2019Europe de l\u2019Est, con\u00e7ue pour accompagner les proc\u00e9d\u00e9s de <a href=\"https:\/\/www.boccard.com\/fr\/solutions\/tekinbio-fermenteur-pour-de-micro-organismes\/\">fermentation<\/a> de l\u2019\u00e9chelle pilote jusqu\u2019\u00e0 des volumes de production plus importants. Le projet comprend trois bior\u00e9acteurs de volumes utiles de 50, 500 et 5 000 litres, une cuve de pr\u00e9paration des milieux de culture de 2 500 litres, des syst\u00e8mes de transfert et les infrastructures de proc\u00e9d\u00e9 n\u00e9cessaires au fonctionnement des bior\u00e9acteurs de mani\u00e8re ind\u00e9pendante ou en cascade.<\/p><p><em>D\u00e9couvrez comment Boccard accompagne un client du secteur des biotechnologies en Europe de l\u2019Est dans le d\u00e9veloppement d\u2019une installation de fermentation flexible et \u00e9volutive, con\u00e7ue pour relier la recherche, le d\u00e9veloppement des proc\u00e9d\u00e9s et la production \u00e0 plus grande \u00e9chelle.<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-38fa0fd elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"38fa0fd\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-756b356\" data-id=\"756b356\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0eaa65d elementor-widget elementor-widget-heading\" data-id=\"0eaa65d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><b>Du d\u00e9veloppement des proc\u00e9d\u00e9s \u00e0 l\u2019augmentation des capacit\u00e9s de fermentation<\/b><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b5cf95f elementor-widget elementor-widget-text-editor\" data-id=\"b5cf95f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"CellBody\"><span lang=\"EN-US\">Les trois \u00e9chelles de<\/span> <a href=\"https:\/\/www.boccard.com\/fr\/solutions\/tekinbio-fermenteur-pour-de-micro-organismes\/\">bior\u00e9acteurs TEKINBIO\u2122<\/a> <span lang=\"EN-US\">visent \u00e0 assurer une continuit\u00e9 entre les premi\u00e8res \u00e9tapes de d\u00e9veloppement des proc\u00e9d\u00e9s et des lots de production plus importants. Chaque cuve peut fonctionner de mani\u00e8re ind\u00e9pendante, tandis que le fonctionnement en cascade est con\u00e7u pour permettre le transfert de mati\u00e8re entre les \u00e9chelles successives.<\/span><\/p><p class=\"CellBody\">Cette configuration offre au futur utilisateur plusieurs possibilit\u00e9s d\u2019exploitation : d\u00e9velopper des proc\u00e9d\u00e9s \u00e0 diff\u00e9rents volumes, pr\u00e9parer l\u2019inoculum pour une cuve de plus grande capacit\u00e9 et mener des fermentations distinctes selon les besoins de recherche ou de production.<\/p><p class=\"CellBody\"><span lang=\"EN-US\">L\u2019installation est \u00e9galement <a href=\"https:\/\/www.boccard.com\/fr\/solutions\/ingenierie-travaux-neufs\/\">con\u00e7ue<\/a> pour accueillir des proc\u00e9d\u00e9s aux profils op\u00e9ratoires vari\u00e9s, allant de cycles courts en mode batch \u00e0 des campagnes de fermentation prolong\u00e9es. L\u2019objectif est de proposer une plateforme commune capable de s\u2019adapter \u00e0 l\u2019\u00e9volution des applications biotechnologiques, sans n\u00e9cessiter une installation distincte pour chaque \u00e9chelle.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t<div class=\"elementor-element elementor-element-d327f84 e-flex e-con-boxed e-con e-parent\" data-id=\"d327f84\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7ee7000 elementor-widget elementor-widget-image\" data-id=\"7ee7000\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"511\" src=\"https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_3_EN_11_26-1024x654.png\" class=\"attachment-large size-large wp-image-95823\" alt=\"\" srcset=\"https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_3_EN_11_26-1024x654.png 1024w, https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_3_EN_11_26-300x192.png 300w, https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_3_EN_11_26-768x490.png 768w, https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_3_EN_11_26.png 1167w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2e6aa00 elementor-widget elementor-widget-text-editor\" data-id=\"2e6aa00\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\"><em>Figure 1. Rendu 3D de<\/em> <em>l&rsquo;installation de fermentation multi-bior\u00e9acteurs, de 50 \u00e0 5 000 L<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-944db71 e-flex e-con-boxed e-con e-parent\" data-id=\"944db71\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3a52c49 elementor-widget elementor-widget-heading\" data-id=\"3a52c49\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><b>Contr\u00f4le des proc\u00e9d\u00e9s et automatisation int\u00e9gr\u00e9s<\/b><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-379d5b9 elementor-widget elementor-widget-text-editor\" data-id=\"379d5b9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"CellBody\"><a href=\"https:\/\/www.boccard.com\/fr\/solutions\/electricite-instrumentation-automatismes\/\">L\u2019automatisation<\/a> constitue un axe central du projet. L\u2019architecture de contr\u00f4le est en cours de d\u00e9veloppement pour coordonner les trois bior\u00e9acteurs, la pr\u00e9paration des milieux de culture, les transferts, le dosage, la r\u00e9gulation de temp\u00e9rature, la gestion des gaz, les op\u00e9rations de nettoyage et l\u2019analyse des proc\u00e9d\u00e9s.<\/p><p class=\"CellBody\">Chaque bior\u00e9acteur est con\u00e7u avec une instrumentation permettant le suivi du pH, de l\u2019oxyg\u00e8ne dissous, de la temp\u00e9rature et de la biomasse, ainsi qu\u2019une filtration des gaz et une unit\u00e9 d\u00e9di\u00e9e de r\u00e9gulation de temp\u00e9rature. Le p\u00e9rim\u00e8tre analytique comprend \u00e9galement la mesure du CO\u2082, de l\u2019O\u2082 et de l\u2019\u00e9thanol, compl\u00e9t\u00e9e par des syst\u00e8mes d\u00e9di\u00e9s de dosage des additifs de proc\u00e9d\u00e9.<\/p><p class=\"CellBody\"><span lang=\"EN-US\">Les <a href=\"https:\/\/www.boccard.com\/fr\/solutions\/gestion-de-projet-industriel\/\">\u00e9quipes projet<\/a> affinent les exigences fonctionnelles avec le client tout au long de la r\u00e9alisation, afin que les s\u00e9quences op\u00e9ratoires, les interfaces, les alarmes et les fonctions de proc\u00e9d\u00e9 restent en ad\u00e9quation avec l\u2019utilisation pr\u00e9vue de l\u2019installation.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b29327c elementor-widget elementor-widget-heading\" data-id=\"b29327c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><b>Une installation modulaire con\u00e7ue pour l\u2019espace limit\u00e9<\/b><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9a7011d elementor-widget elementor-widget-text-editor\" data-id=\"9a7011d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"CellBody\">L\u2019installation est d\u00e9velopp\u00e9e autour de skids de proc\u00e9d\u00e9 modulaires et d\u2019une pr\u00e9fabrication pouss\u00e9e en Pologne. La <a href=\"https:\/\/www.boccard.com\/fr\/solutions\/ingenierie-travaux-neufs\/\">conception 3D<\/a> avanc\u00e9e permet de d\u00e9finir l\u2019implantation des cuves, des tuyauteries, des vannes et des zones d\u2019acc\u00e8s avant la livraison sur le site du client en Europe de l\u2019Est.<\/p><p class=\"CellBody\">Cette approche vise \u00e0 limiter le montage sur site, \u00e0 am\u00e9liorer l\u2019encha\u00eenement des op\u00e9rations d\u2019installation et \u00e0 faciliter une mise en service ma\u00eetris\u00e9e. La conception prend \u00e9galement en compte les exigences d\u2019hygi\u00e8ne, la vidangeabilit\u00e9, la nettoyabilit\u00e9 et les acc\u00e8s n\u00e9cessaires \u00e0 l\u2019exploitation et \u00e0 la maintenance dans l\u2019espace disponible.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4493192 e-flex e-con-boxed e-con e-parent\" data-id=\"4493192\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5d9f6a5 elementor-widget elementor-widget-image\" data-id=\"5d9f6a5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"721\" src=\"https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_4_EN_11_26-1024x923.jpg\" class=\"attachment-large size-large wp-image-95824\" alt=\"\" srcset=\"https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_4_EN_11_26-1024x923.jpg 1024w, https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_4_EN_11_26-300x270.jpg 300w, https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_4_EN_11_26-768x692.jpg 768w, https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_4_EN_11_26-1536x1384.jpg 1536w, https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_4_EN_11_26-2048x1845.jpg 2048w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ee3c757 elementor-widget elementor-widget-text-editor\" data-id=\"ee3c757\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\"><em>Figure 2. Vue de l&rsquo;installation compos\u00e9e de modules de proc\u00e9d\u00e9 pr\u00e9fabriqu\u00e9s<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-dc14d1c e-flex e-con-boxed e-con e-parent\" data-id=\"dc14d1c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7ac26eb elementor-widget elementor-widget-image\" data-id=\"7ac26eb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"800\" src=\"https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_5_EN_11_26-1024x1024.jpg\" class=\"attachment-large size-large wp-image-95825\" alt=\"\" srcset=\"https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_5_EN_11_26-1024x1024.jpg 1024w, https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_5_EN_11_26-300x300.jpg 300w, https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_5_EN_11_26-150x150.jpg 150w, https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_5_EN_11_26-768x768.jpg 768w, https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_5_EN_11_26-1536x1536.jpg 1536w, https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_5_EN_11_26-2048x2048.jpg 2048w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c0373ec elementor-widget elementor-widget-text-editor\" data-id=\"c0373ec\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\"><em>Figure 3. Vue de la tuyauterie et des vannes de l\u2019installation reliant les diff\u00e9rents modules<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-560b7be e-flex e-con-boxed e-con e-parent\" data-id=\"560b7be\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-083b605 elementor-widget elementor-widget-heading\" data-id=\"083b605\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><b>Utilit\u00e9s et utilisation efficace des ressources prises en compte d\u00e8s la conception<\/b><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-25509c3 elementor-widget elementor-widget-text-editor\" data-id=\"25509c3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>L\u2019utilisation efficace des ressources est prise en compte d\u00e8s l\u2019ing\u00e9nierie, plut\u00f4t qu\u2019apr\u00e8s l\u2019installation. La conception actuelle pr\u00e9voit la r\u00e9cup\u00e9ration des condensats pour la production de vapeur de proc\u00e9d\u00e9 et la r\u00e9utilisation de certains fluides de nettoyage dans d\u2019autres parties de l\u2019installation apr\u00e8s une d\u00e9contamination appropri\u00e9e.<\/p><p>Le choix des \u00e9quipements et des vannes repose sur les param\u00e8tres r\u00e9els du proc\u00e9d\u00e9 et les besoins en utilit\u00e9s. Ce travail d\u2019ing\u00e9nierie vise \u00e0 concilier les performances du proc\u00e9d\u00e9, la conception hygi\u00e9nique, la consommation d\u2019\u00e9nergie et la fiabilit\u00e9 de fonctionnement aux diff\u00e9rentes \u00e9chelles de bior\u00e9acteurs.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4bf212d e-flex e-con-boxed e-con e-parent\" data-id=\"4bf212d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-628a34e elementor-widget elementor-widget-heading\" data-id=\"628a34e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><b>Un projet biotechnologique collaboratif pilot\u00e9 par Boccard<\/b><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-708a5cc elementor-widget elementor-widget-text-editor\" data-id=\"708a5cc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Le projet mobilise des technologues de proc\u00e9d\u00e9s, des <a href=\"https:\/\/www.boccard.com\/fr\/solutions\/ingenierie-travaux-neufs\/\">concepteurs m\u00e9caniques et 3D,<\/a> des <a href=\"https:\/\/www.boccard.com\/fr\/solutions\/electricite-instrumentation-automatismes\/\">automaticiens,<\/a> des <a href=\"https:\/\/www.boccard.com\/fr\/solutions\/prefabrication-de-skids\/\">\u00e9quipes de production<\/a> et d\u2019installation, des <a href=\"https:\/\/www.boccard.com\/fr\/solutions\/cle-en-main-epcm\/\">sp\u00e9cialistes des achats et les expertises<\/a> de l\u2019ensemble de Boccard.<\/p><p>En associant plusieurs \u00e9chelles de fermentation, l\u2019automatisation des proc\u00e9d\u00e9s, <a href=\"https:\/\/www.boccard.com\/fr\/solutions\/stations-nep-et-sep\/\">l\u2019ing\u00e9nierie hygi\u00e9nique<\/a> et la fabrication modulaire, Boccard Polska accompagne le client dans le d\u00e9veloppement d\u2019une plateforme de fermentation <a href=\"https:\/\/www.boccard.com\/fr\/solutions\/tekinbio-fermenteur-pour-de-micro-organismes\/\">TEKINBIO\u2122<\/a> polyvalente pour ses futures activit\u00e9s biotechnologiques.<\/p><p class=\"CellBody\">Le projet renforce \u00e9galement la capacit\u00e9 de Boccard \u00e0 fournir des installations de fermentation int\u00e9gr\u00e9es reliant le d\u00e9veloppement des proc\u00e9d\u00e9s \u00e0 la production \u00e0 plus grande \u00e9chelle. Des informations compl\u00e9mentaires pourront \u00eatre communiqu\u00e9es lorsque le projet aura atteint le stade appropri\u00e9 et que la communication aura \u00e9t\u00e9 convenue avec le client.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b637be1 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b637be1\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-db882d4\" data-id=\"db882d4\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-044c6e7 e-transform elementor-cta--skin-classic elementor-animated-content elementor-bg-transform elementor-bg-transform-zoom-in elementor-widget elementor-widget-call-to-action\" data-id=\"044c6e7\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"call-to-action.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-cta\">\n\t\t\t\t\t<div class=\"elementor-cta__bg-wrapper\">\n\t\t\t\t<div class=\"elementor-cta__bg elementor-bg\" style=\"background-image: url(https:\/\/www.boccard.com\/wp-content\/uploads\/2026\/10\/Tekinbio_Case_Study_4_2_EN_11_26-1024x966.jpg);\" role=\"img\" aria-label=\"Tekinbio_Case_Study_4_2_EN_11_26\"><\/div>\n\t\t\t\t<div class=\"elementor-cta__bg-overlay\"><\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-cta__content\">\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h2 class=\"elementor-cta__title elementor-cta__content-item elementor-content-item\">\n\t\t\t\t\t\tEn savoir plus sur nos solutions pour<br \/>la fermentation et l'Agro-alimentaire et ingr\u00e9dients ?\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-cta__button-wrapper elementor-cta__content-item elementor-content-item \">\n\t\t\t\t\t<a class=\"elementor-cta__button elementor-button elementor-size-\" href=\"https:\/\/www.boccard.com\/fr\/contact\/\">\n\t\t\t\t\t\tContactez-nous\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-415afe6 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"415afe6\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2edeb26\" data-id=\"2edeb26\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bcd2852 elementor-widget elementor-widget-heading\" data-id=\"bcd2852\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><b>Points cl\u00e9s<\/b><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-77fb1bf barre elementor-widget elementor-widget-heading\" data-id=\"77fb1bf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/www.boccard.com\/fr\/solutions\/tekinbio-fermenteur-pour-de-micro-organismes\/\">3 bior\u00e9acteurs TEKINBIO\u2122 de volumes utiles de 50, 500 et 5 000 L, con\u00e7us pour accompagner le changement d\u2019\u00e9chelle en fermentation, du d\u00e9veloppement des proc\u00e9d\u00e9s \u00e0 des lots de production plus importants.<\/a><\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-335f23d barre elementor-widget elementor-widget-heading\" data-id=\"335f23d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Modes de fonctionnement <b>ind\u00e9pendants et en cascade,<\/b> avec transfert du produit entre les bior\u00e9acteurs successifs.<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e8a6440 barre elementor-widget elementor-widget-heading\" data-id=\"e8a6440\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><b>Suivi du pH, de l\u2019oxyg\u00e8ne dissous, de la temp\u00e9rature et de la biomasse,<\/b> compl\u00e9t\u00e9 par l\u2019analyse du CO\u2082, de l\u2019O\u2082 et de l\u2019\u00e9thanol.<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-410d017 barre elementor-widget elementor-widget-heading\" data-id=\"410d017\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><b>Automatisation int\u00e9gr\u00e9e des proc\u00e9d\u00e9s,<\/b> coordonnant la pr\u00e9paration des milieux de culture, les transferts, le dosage et le nettoyage, avec une station NEP et sa boucle de nettoyage.<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-58a81d5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"58a81d5\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-cb6d518\" data-id=\"cb6d518\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-86b2451 elementor-widget elementor-widget-heading\" data-id=\"86b2451\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Scope : P\u00c9RIM\u00c8TRE DES TRAVAUX, \u00c9QUIPEMENTS ET SERVICES FOURNIS<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8f93e77 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8f93e77\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-edbf430\" data-id=\"edbf430\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-858bf2a elementor-widget elementor-widget-text-editor\" data-id=\"858bf2a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li><strong><a href=\"https:\/\/www.boccard.com\/fr\/solutions\/genie-des-procedes\/\">Ing\u00e9nierie<\/a> et <a href=\"https:\/\/www.boccard.com\/fr\/solutions\/prefabrication-de-skids\/\">pr\u00e9fabrication de skids:<\/a><\/strong> Ing\u00e9nierie des proc\u00e9d\u00e9s, conception 3D et d\u00e9veloppement de skids modulaires, avec une pr\u00e9fabrication pouss\u00e9e en Pologne et une implantation des \u00e9quipements adapt\u00e9e \u00e0 l\u2019espace disponible.<\/li><li><strong><a href=\"https:\/\/www.boccard.com\/fr\/solutions\/tekinbio-fermenteur-pour-de-micro-organismes\/\">\u00c9quipements de fermentation:<\/a><\/strong> <strong>3 bior\u00e9acteurs de TEKINBIO\u2122<\/strong> de <strong>50, 500 et 5 000 L, <\/strong>une <strong>cuve de pr\u00e9paration des milieux de culture de 2 500 L<\/strong> et des syst\u00e8mes de transfert du produit pour un fonctionnement ind\u00e9pendant ou en cascade.<\/li><li><a href=\"https:\/\/www.boccard.com\/fr\/solutions\/electricite-instrumentation-automatismes\/\"><strong>Instrumentation et automatisation:<\/strong><\/a> Contr\u00f4le int\u00e9gr\u00e9 de la fermentation, de la pr\u00e9paration des milieux de culture, des transferts et du dosage, avec des unit\u00e9s d\u00e9di\u00e9es de r\u00e9gulation de temp\u00e9rature, des capteurs de proc\u00e9d\u00e9 et des <strong>analyseurs de CO\u2082, d\u2019O\u2082 et d\u2019\u00e9thanol.<\/strong><\/li><li><strong><a href=\"https:\/\/www.boccard.com\/fr\/solutions\/stations-nep-et-sep\/\">\u00c9quipements de nettoyage:<\/a><\/strong> <strong>Station de nettoyage en place (NEP)<\/strong> avec boucle de nettoyage, int\u00e9gr\u00e9e \u00e0 une installation con\u00e7ue pour r\u00e9pondre aux exigences d\u2019hygi\u00e8ne, de vidangeabilit\u00e9 et de nettoyabilit\u00e9.<\/li><li>Int\u00e9gration des utilit\u00e9s : Dispositions pr\u00e9vues pour la r\u00e9cup\u00e9ration des condensats destin\u00e9s \u00e0 la 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elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3dbdff30\" data-id=\"3dbdff30\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-26d61c56 elementor-hidden-mobile elementor-widget elementor-widget-spacer\" data-id=\"26d61c56\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Boccard d\u00e9veloppe une installation multi-bior\u00e9acteurs destin\u00e9e \u00e0 accompagner le scale up des proc\u00e9d\u00e9s de fermentation, de 50 \u00e0 5 000 litres. Les modes de fonctionnement, ind\u00e9pendants ou en cascade, associ\u00e9s \u00e0 une automatisation int\u00e9gr\u00e9e, facilitent le d\u00e9veloppement des proc\u00e9d\u00e9s ainsi que la production \u00e0 plus grande \u00e9chelle.<\/p>\n","protected":false},"author":29,"featured_media":95821,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[38,72,39],"tags":[],"class_list":["post-95820","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualites","category-alimentation-nutrition","category-realisations"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Scale up en fermentation gr\u00e2ce \u00e0 une installation multi-bior\u00e9acteurs de 50 \u00e0 5 000 L - Boccard<\/title>\n<meta name=\"description\" content=\"D\u00e9couvrez le scale up des proc\u00e9d\u00e9s de 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